Automated tangential flow filtration system

Automate with confidence. Scale without compromise.

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ELEVECTA™ cell line portfolio for AAV manufacturing

Beyond supporting your gene therapy processes with our technology and application knowledge, we're passionate about advancing solutions in areas where the status quo isn’t good enough. That's why we're excited to tell you about our ELEVECTA™ cell lines ― a significant advancement in viral vector manufacturing.

Accelerate scale‑up. Reduce risk. Deliver consistent results.

Cytiva’s automated tangential flow filtration (TFF) systems are designed to help biopharma and biotech manufacturers move faster—from pilot studies to full‑scale production—without compromising quality or compliance.

By combining automation, scalable performance, and cGMP‑ready design, these stainless-steel systems simplify tangential flow filtration workflows while improving productivity and reliability at every stage.

How you benefit:

Scale with confidence: Seamlessly transition from development to manufacturing.
Speed-up your TFF process: Reduce your process time with our automated operation and optimized system design.
Lower risk, built for GMP: A sanitary, fully drainable design with full material traceability.
Work smarter: UNICORN™ software process controlled.
Stay flexible: Compatible with both filter cassettes and hollow fiber cartridges.
Get up and running faster: Standardized configurations and shorter lead times streamline ordering and deployment.
Reduced operator dependency

Discover how our automated TFF systems support your path from pilot to production. Fill in the form below and our specialist will connect with you shortly.

SUPRAdisc™ II depth filter modules

Next generation in depth filter module technology for bioprocess clarification applications.

The SUPRAdisc™ II module design combines the filtration performance of Seitz™ media and the structural robustness of interlocking dual drainage plates.

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Praesent lacus arcu, mollis ut volutpat pharetra, vulputate quis massa. Nam interdum fringilla bibendum.

Sed feugiat libero eu turpis tincidunt iaculis. In vel aliquam est, at porta neque. Donec hendrerit ultrices consectetur. Integer feugiat massa quis arcu ullamcorper, tristique facilisis massa feugiat. Phasellus risus mauris, pretium vitae tortor non, tristique fringilla tortor. Aliquam volutpat eros ac risus consectetur, quis gravida erat lobortis. Quisque id rutrum enim, sed fermentum nisl. Nulla volutpat turpis ac ligula venenatis maximus. In non dui ante.

Morbi faucibus sit amet dolor sit amet cursus. Quisque vulputate tellus in magna eleifend, ut luctus orci commodo.

Praesent tellus neque, maximus sit amet mauris in, fermentum pharetra ante. Sed sit amet nibh commodo, fringilla lectus ac, dictum velit. Aliquam cursus feugiat congue. Aenean sit amet enim massa. Praesent mollis sagittis est, ut accumsan eros lobortis id. Maecenas at libero ex. Proin quis est vitae tortor ullamcorper pretium eu non nunc. Quisque at lacus accumsan, finibus sapien ac, viverra ligula. Donec commodo bibendum elit sit amet posuere. Curabitur rutrum.

The ELEVECTA™ cell line portfolio combines innovative design and deep expertise to deliver transient, packaging, and producer options that provide competitive performance, high quality, and flexibility.

Fit for purpose: Choose the option that makes sense for your stage, asset mix, and organizational goals.
Flexible: Enjoy competitive terms and the freedom to transition between cell lines as needs evolve.
Enhanced product quality*: Minimize host cell DNA inside capsids, which is resistant to nucleases.
Innovative: Access advances in cell line engineering informed by deep industry know-how.
Collaborative: We’re more than a supplier. Benefit from a comprehensive suite of regulatory support services designed to expedite your success in advancing to and through clinical trials.

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Praesent lacus arcu, mollis ut volutpat pharetra, vulputate quis massa. Nam interdum fringilla bibendum. Maecenas non odio dui. Suspendisse eros ex, ullamcorper et dui non.

Sed feugiat libero eu turpis tincidunt iaculis. In vel aliquam est, at porta neque. Donec hendrerit ultrices consectetur. Integer feugiat massa quis arcu ullamcorper, tristique facilisis massa feugiat. Phasellus risus mauris, pretium vitae tortor non, tristique fringilla tortor. Aliquam volutpat eros ac risus consectetur, quis gravida erat lobortis. Quisque id rutrum enim, sed fermentum nisl. Nulla volutpat turpis ac ligula venenatis maximus. In non dui ante. Sed ullamcorper quis nisi.

Morbi faucibus sit amet dolor sit amet cursus. Quisque vulputate tellus in magna eleifend, ut luctus orci commodo.

Praesent tellus neque, maximus sit amet mauris in, fermentum pharetra ante. Sed sit amet nibh commodo, fringilla lectus ac, dictum velit. Aliquam cursus feugiat congue. Aenean sit amet enim massa. Praesent mollis sagittis est, ut accumsan eros lobortis id. Maecenas at libero ex. Proin quis est vitae tortor ullamcorper pretium eu non nunc. Quisque at lacus accumsan, finibus sapien ac, viverra ligula. Donec commodo bibendum elit sit amet posuere. Curabitur rutrum pharetra nisl, vitae tincidunt ante consectetur et.

ELEVECTA™ transient cell line

Preseves flexibility while delivering excellent performance and quality - all aimed at quickly advancing candidates to clinical trials.

Excellent performance: Achieve high titers of infectious virus, which you can boost further by using enhancers.
Enhanced product quality*: Minimize DNase-resistant host cell DNA inside capsids.
Innovative: Access advances in cell line engineering across the entire portfolio to support transition between cell lines.
Collaborative: Benefit from a comprehensive suite of regulatory support services.

ELEVECTA™ packaging cell line

Contains all genes except the transgene; allows streamlining the screaning of assets that use the same capsid to target the same tissue type.

Streamlined screening: Efficiently screen multiple assets that target the same tissue type.
Cost-effective approach: Reduce your plasmid costs with single-plasmid transfection compared with triple transfection.
One cell line to clinic: Go to clinic with one cell line and simplify your regulatory asks when you’re targeting the same tissue type across your programs.

ELEVECTA™ producer cell line

Contains all genes to produce AAV; simply induce. The result is a simplified, robust, upstream process that easily scales to treat hundreds of thousands.

Simplified manufacturing process: Replace multi-step transfection with one-step induction.
Easy scalability: Scale up seamlessly to achieve large quantities of AAV material.
Enhanced reproducibility: Produce AAV from a monoclonal cell line, enabling batch-to-batch consistency.
Reduced COGS: Skip the need for transfection reagent and any plasmid DNA, which are the most expensive raw materials.