Join us at Fraunhofer Institute for Cell Therapy and Immunology IZI on 28–29 August where the spotlight will be on adeno-associated virus (AAV) and protein production and equipment: ÄKTA™ systems plus imaging and Biacore™ systems.

Engage in scientific presentations, hands-on sessions with Cytiva equipment, and take the opportunity to take a tour through the institute.



Where we’ll host you:

Fraunhofer-Institut für Zelltherapie und Immunologie IZI

Perlickstr. 1, 04103 Leipzig, Germany


In collaboration with:


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Register to attend

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Speakers and topics

The gallery of speakers invited to host talks and speak to you on all things SPR, along with the subject area they will be coming to speak about. This list will be updated with each new wave of speaker announcements.

  • Phil Addis, Sygnature Discovery - Pushing the limits: Establishing scalable SPR assays for molecular glue discovery
  • Jason Baardsnes, National Research Council Canada - SARS Cov2 – Ace2 binding assays for kinetics, selection and QC
  • Aurelie Castan, Novartis Pharma AG - Characterization of antibody binding to FcɣRIIIa by SPR and affinity chromatography MS
  • Göran Dahl, AstraZeneca
  • Gregory Descrescenzo, Montreal Poltyech
  • Tim van den Hooven, Genmab - FcRn characterization: an odyssey to (and through) qualification
  • Ute Jucknischke, Roche Diagnostics - Kinetics with native biomarkers – The reality check for antibodies
  • David Kallenberg, UCB - Fragment screening on the Biacore 8K+ and an evaluation of the Biacore Intelligent Analysis™ machine learning software
  • Matthias Kania, Boeringer Ingelheim Pharma GmbH & Co. K - Applications of Biacore technology in a regulated biopharmaceutical environment
  • Matthias Knape, Boeringer Ingelheim Pharma GmbH & Co. K - Applications of Biacore technology in a regulated biopharmaceutical environment
  • Patrik Nygren, BioArctic
  • Dr. Hanno Sjuts, Sanofi
  • Pedro M.F. Sousa, iBet - Extract2chip - Bypassing protein purification in drug discovery using SPR
  • Rob Staehlin, Purdue University - Lipid-protein interactions in virus assembly, budding and virus spread
  • David Zollman, University of Dundee - Expanding the biophysical toolbox for targeted protein degradation drug discovery

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Agenda

Subject to minor changes leading up to the event date.

Time Event Speaker
09:00 - 09:15 Welcome Prof. Dr. Ulrike Köhl (Fraunhofer IZI)
09:15 - 09:30 Introduction Marialuisa Casamenti (Cytiva)
09:30 - 10:15 AAV purification – tools and digital solutions for an efficient and robust separation Lutz Mathe (Cytiva) and Franco Klingberg (Cytiva)
10:15 - 10:45 Design of experiments is important for scientific improvements Dr. Peter Paul Heym (Sum Of Squares – Statistical Consulting)
10:45 - 11:00 Q&A
11:00 - 11:30 Tips for straightforward protein chromatography Stephanie Runde (Cytiva)
11:30 - 11:45      Optimization of purification processes using Amersham™ ImageQuant™ 800 and IQTL analysis software Linda Keller (Cytiva)
11:45 - 12:45 Hands-on Q&A featuring Biacore™, ÄKTA™, imaging systems, and institute tour
12:45 - 13:45 Break
13:45 - 14:45 More hands-on Q&A and institute tour
14:45 - 15:15 From transient to stable: How cell lines influence AAV manufacturing and product quality Mischa Schwendy (Cytiva)
15:15 - 15:45 Generation of monoclonal antibodies: accompanied by SPR and ELISA Dr. Martin Kleinschmidt (Fraunhofer IZI)
15:45 Q&A
Time Event Speaker
9:00 - 11:00 In-depth, hands-on session for protein purification
11:00 - 13:00 Individual conversations. Interested? Book yours in advance via the registration form

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Excellent performance

Achieve high titers of infectious virus, which you can boost further by using enhancers.

Enhanced product quality

Minimize DNase-resistant host cell DNA inside capsids.

Innovative

Access advances in cell line engineering across the entire portfolio to support transition between cell lines.

Collaborative

Benefit from a comprehensive suite of regulatory support services.

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Excellent performance

Achieve high titers of infectious virus, which you can boost further by using enhancers.

Enhanced product quality

Minimize DNase-resistant host cell DNA inside capsids.

Innovative

Access advances in cell line engineering across the entire portfolio to support transition between cell lines.

Collaborative

Benefit from a comprehensive suite of regulatory support services.

ELEVECTA packaging cell line. Contains all genes except the transgene. Allows streamlining the screening of assets that use the same capsid to target the same tissue type.

Streamlined screening

Efficiently screen multiple assets that target the same tissue type.

Cost-effective approach

Reduce your plasmid costs with single-plasmid transfection compared with triple transfection.

One cell line to clinic

Go to clinic with one cell line and simplify your regulatory asks when you’re targeting the same tissue type across your programs.


CAR T and TCR manufacturing


We are looking forward to seeing you at ISCT. Join us for an exciting new product reveal over a glass of champagne on “date and time” If you are working in cell therapy, check out all the sessions showcasing what’s next in autologous CAR T and TCR manufacturing.

Product showcase

An introduction of the new, end-to-end solution from Cytiva to manufacture autologous CAR T therapies at commercial scale.
Presenters: Stephanie Bourin, Senior Product Manager at Cytiva and Bertrand Foucaut, Senior Product Manager at Cytiva

Corporate session

Thursday 30 May, 6-7 PM
Deliver what's next: fueling the future of autologous CAR T therapy
Emmanuel Abate, President Genomic Medicine at Cytiva; George White, Cell Therapy Product Management Leader at Cytiva; Beate Mueller-Tiemann, Chief Technology Officer at Cytiva; Sadik Kassim, Chief Technology Officer at Danaher; Angela Johnson, Global Regulatory and Compliance Leader, Cytiva; KITE and OMNIA BIO

Poster

End-to-end manufacturing of autologous CAR T cell therapies with a new cell therapy manufacturing platform.
More details to come.
Presenters: Federico Franchi, R& Manager MBO Biology and Marine De Lageneste, Biology lead Senior Scientist

New product demos

An introduction of the new, end-to-end solution from Cytiva to manufacture autologous CAR T therapies at commercial scale.
Presenters: Stephanie Bourin, Senior Product Manager at Cytiva and Bertrand Foucaut, Senior Product Manager at Cytiva

Can't make it to ISCT? Join us on 13 June to discover what’s next in autologous CAR T manufacturing: LINK TO VIRTUAL LAUNCH REGISTRATION PAGE

Beyond CAR T


Interested in what's next?

Launch and patient access concurrent session

Friday 31 May 2024, 3:45-4:45 PM
Industrializing manufacturing and distribution
Martin Westberg, Vice President, Cell Therapy, Cytiva

Posters

Regulatory T cell expansion in the Xuri™ cell expansion system W25
Presenter: Mojtaba Parvizi, Global Fast Trak Leader — Cell Therapy

Closed, semi-automated harvest of iPSC scale-up workflow using the Sepax™ C-Pro with CultureWash protocol
Presenter: Mojtaba Parvizi, Global Fast Trak Leader — Cell Therapy

RNA-LNP


Are you working on RNA-LNPs? Discover the potential of our solutions from concept to clinic.

Product showcase

Friday 31 May, 12:30-12:45 PM
Precision NanoSystems, now part of Cytiva
Samuel Clarke, Director R&, Precision NanoSystems – now part of Cytiva.

Posters

Optimization of multiplex CRISPR-Cas9 editing of human primary T cells using lipid nanoparticles (LNPs) and subsequent off-target evaluation
Meenakshi Swaminathan, Associate Scientist, Product Development, Cytiva

Strategies for producing clinical and commercial RNA-LNP drug products
Robert Young, Senior Engineer, Systems, Cytiva

Oral abstract presentation

Efficient gene editing in CD34+ hematopoietic stem and progenitor cells using non-viral lipid nanoparticles
Stella Park, Associate Scientist, Product Development, Cytiva

Aseptic Filling


Are you interested in Aseptic Filling?

Global showcase presentation

Thursday 30 May, 1:15-1:30 PM, Theatre A Slot: 10A
New containment solutions for automated aseptic filling for gene therapy

Presenters: Jim Thompson, Director of R&, West Pharmaceutical Services and Brent Lieffers, Senior Director of Innovation Advocacy, Cytiva

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