TIL therapy manufacturing

Addressing challenges at each stage of the workflow

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What to know at each stage of your TIL therapy manufacturing workflow

TIL therapies offer great promise—but come with unique manufacturing complexities. From tumor tissue handling to expansion and delivery, each stage introduces specific risks that can impact consistency, scalability, and patient outcomes.

This infographic breaks down the full workflow and outlines common roadblocks—along with solutions designed to support robust, streamlined, and controlled TIL production.

Key stages addressed:

  • Tumor tissue resection and transfer
  • Tissue disaggregation and feeder cells
  • Selection and expansion (pre-REP)
  • TIL activation and expansion (REP)
  • Harvest and formulation
  • Cryopreservation and shipment
  • Therapy delivery

Cytiva™ Protein Select™ resin

A new affinity chromatography resin

Cytiva™ Protein Select™ resin is an affinity chromatography resin for purifying recombinant proteins using the self-cleaving Cytiva™ Protein Select™ tag. During an affinity step performed with Cytiva™ Protein Select™ resin, the protein self-cleaves from the tag and elutes with no residual tag amino acids.

  • This technology simplifies tagged protein purification when used in research.
  • It standardizes purification during process development and later phases of any protein that does not have an affinity binding partner.

SUPRAdisc™ II depth filter modules

Next generation in depth filter module technology for bioprocess clarification applications.

The SUPRAdisc™ II module design combines the filtration performance of Seitz™ media and the structural robustness of interlocking dual drainage plates.

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