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Choose a PUPSIT solution that suits the way you work

Manual:

  • Standardized installation
  • Easy to use
  • Configurable design

Automated:

  • Consistent processing
  • Enhanced product recovery
  • Integrates into your existing control system

Standard filter sets:

  • Shorter lead times
  • Simplified development and testing
  • Optimized designs

Find out more today!

Pre-use post-sterilization integrity testing

PUPSIT

Dedicated products, implementation services and ongoing support to help you achieve your goals.

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What is PUPSIT, and why does it matter?

PUPSIT helps ensure the sterility of aseptically-filled medicinal drug products. It determines the integrity of the sterilizing-grade filter and assembly, including filter housing, support structure, and connections, after the assembly has been installed and sterilized but before it is used to filter product.

PUPSIT guards against filter damage during shipping, handling, installation, and sterilization prior to use. A damaged filter could result in a non-sterile product, which can ultimately affect drug safety.

Meet our range of PUPSIT solutions

Implementing PUPSIT effectively requires a delicate balance.

Work with Cytiva’s process development team to get it right from the start. Our manual, automated and custom solutions and ongoing support help give you peace of mind as you implement PUPSIT.

Get your tailored solution…

13 Points to consider when selecting your next filter integrity test instrument

Choosing the right filter integrity test instrument, tailored to your needs, can be a difficult task. An informed decision will help ensure seamless integration of the instrument into your critical processes.

Process needs for filter integrity test instruments have changed over the years as regulations, technologies and best practice have evolved to improve patient safety. Our updated selection guide outlines important criteria to help you compare and evaluate your options when choosing a filter integrity test instrument.

Download the guide to learn more about:

  • Regulations applicable to filter integrity test instruments including:
    • Data integrity and data access control
    • Good automated manufacturing practice (GAMP)
    • EU and FDA Good manufacturing practice (GMP)
  • ​How to choose the filter tests and features which are critical for your process, including forward flow (diffusive), water intrusion and bubble point testing
  • A set of 13 criteria which can be used to compare and evaluate different instruments, including our Palltronic® Flowstar V filter integrity test instrument

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