Growth in the formulation of drugs suitable for delivery by subcutaneous injection has highlighted potential manufacturing challenges. These challenges are associated with the higher concentration of active ingredients and formulation excipients required to achieve the low dose volumes delivered to patients.

Challenges such as:
  • Optimization of drug formulation to ensure bioavailability of the active ingredient
  • Increased viscosity affecting ultrafiltration, filtration, and fill and finish operations
Solutions that maintain quality, maximize process yield and product recovery are available and can be introduced to adapt an existing manufacturing platform.

Download the white paper and learn more about the key manufacturing challenges associated with the development of high concentration monoclonal antibody (mAb) therapies.

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Acrodisc® Syringe Filters
Reliable Results with Superior Protection

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Follow our connected mAb perfusion process

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Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020

Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .

Publish date: 29 September, 2020
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