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Choose the Perfect Filter Integrity Tester

Check out our guide: “13 Points to consider when selecting your next filter integrity test instrument”.

Fill out the form to get the guide

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A new way to boost pDNA recovery

Optimize your downstream process with a proven approach to plasmid DNA purification and pDNA production.

Fill out the form to access the full poster and discover
how to improve your plasmid DNA purification process today

High-quality plasmid DNA (pDNA) is essential for next-generation therapeutics - viral vectors, mRNA therapies, and DNA vaccines all depend on its yield and purity. However, traditional plasmid DNA extraction and purification kits often underperform during the elution phase, limiting recovery.

Download our exclusive technical poster to explore a proven method that:

  • Boosts pDNA recovery from ~50% to over 90%
  • Uses safe, effective additives arginine and urea to enhance yield and purity
  • Improves resolution of RNA and other impurities
  • Is backed by a robust design of experiments (DoE) strategy


Whether you're optimizing a lab-scale plasmid prep or scaling for cGMP pDNA manufacturing, this poster provides actionable insights to improve your plasmid DNA isolation and purification workflow.

SUPRAdisc™ II depth filter modules

Next generation in depth filter module technology for bioprocess clarification applications.

The SUPRAdisc™ II module design combines the filtration performance of Seitz™ media and the structural robustness of interlocking dual drainage plates.

13 Points to consider when selecting your next filter integrity test instrument

Choosing the right filter integrity test instrument, tailored to your needs, can be a difficult task. An informed decision will help ensure seamless integration of the instrument into your critical processes.

Process needs for filter integrity test instruments have changed over the years as regulations, technologies and best practice have evolved to improve patient safety. Our updated selection guide outlines important criteria to help you compare and evaluate your options when choosing a filter integrity test instrument.

Download the guide to learn more about:

  • Regulations applicable to filter integrity test instruments including:
    • Data integrity and data access control
    • Good automated manufacturing practice (GAMP)
    • EU and FDA Good manufacturing practice (GMP)
  • ​How to choose the filter tests and features which are critical for your process, including forward flow (diffusive), water intrusion and bubble point testing
  • A set of 13 criteria which can be used to compare and evaluate different instruments, including our Palltronic® Flowstar V filter integrity test instrument

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