GE Healthcare Life Sciences is now Cytiva

On-demand webinar

Challenge analytical complexity: 
Biacore SPR systems for candidate selection, characterization, and quality control

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Challenge analytical complexity–Biacore SPR systems for candidate selection, characterization, and quality control

By Michael Murphy, PhD. Cytiva, Marlborough, MA, USA

Biotherapeutic drugs, such as monoclonal antibodies, are large, complex biomolecules whose structural features can impact their biological activity. Several molecular interactions contribute to antibody function and an array of assays are used to select, characterize, and monitor critical quality attributes (CQA) throughout the development process.

Biacore systems for label-free binding assays are used extensively in the biotherapeutic antibody discovery, from development to quality control, giving information for a wide range of applications such as binding, affinity, kinetics, epitope binning, concentration, potency, stability, and many more.

In this webinar we present the utility of Biacore systems at all stages of the process from selection of first candidates to clinical lead. We show that a combination of Biacore instruments, software, sensor chips, and kits support the setup of screening and characterization assays, reduces assay development efforts, and shorten and streamline the time to results for decisive decisions.

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About Michael Murphy

Michael Murphy joined the Biacore team in 2004 to work as a Biacore Application Scientist for GE Healthcare Life Sciences (now Cytiva) in the mid-Atlantic region of the United States. Prior to that, worked with Biacore technology for 4 years as a customer on the development and characterization of aptamers at the Berkeley Lab’s Joint Genome Institute. Received Ph.D. in biophysics from Case Western Reserve University in 2000



About Michael Murphy

Michael Murphy joined the Biacore team in 2004 to work as a Biacore Application Scientist for GE Healthcare Life Sciences (now Cytiva) in the mid-Atlantic region of the United States. Prior to that, he worked with Biacore technology for 4 years as a customer on the development and characterization of aptamers at the Berkeley Lab’s Joint Genome Institute. Received Ph.D. in biophysics from Case Western Reserve University in 2000.



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Lorem ipsum dolor sit amet, consectetur adipisicing elit. Repellendus aliquid tempore natus voluptates repudiandae, eos dolorem libero inventore, quod incidunt, asperiores. Reiciendis itaque enim pariatur, blanditiis minima autem quo a nulla, obcaecati quis, excepturi atque ab rerum! Sequi molestias vel eum, hic, perspiciatis eius suscipit reprehenderit molestiae vitae similique.

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Lorem ipsum dolor sit amet, consectetur adipisicing elit. Repellendus aliquid tempore natus voluptates repudiandae, eos dolorem libero inventore, quod incidunt, asperiores. Reiciendis itaque enim pariatur, blanditiis minima autem quo a nulla, obcaecati quis, excepturi atque ab rerum! Sequi molestias vel eum, hic, perspiciatis eius suscipit reprehenderit molestiae vitae similique.